Anti-pro-caspase-3抗体,半胱天冬酶3酶原抗体 返回列表页

     Anti-pro-caspase-3抗体,半胱天冬酶3酶原抗体产品详细资料

英文名称:Caspase 3 precursor
中文名称:半胱天冬酶-3酶原抗体

产品编号:YK-2593R
产品别名:Caspase 3 precursor; APOPAIN; CASP3; Caspase 3 apoptosis related cysteine protease; Caspase3; CPP32; CPP32B; Cysteine protease CPP32; Human cysteine protease CPP32 isoform alpha mRNA complete cds; PARP cleavage protease; SCA 1; SCA1; SREBP cleavage activity 1; Yama; CASP3_HUMAN; Caspase-3; CASP-3; Apopain; Protein Yama; SREBP cleavage activity 1; SCA-1.  

研究领域 细胞生物  神经生物学  信号转导  细胞凋亡      

抗体来源 Mouse or Rabbit

克隆类型 Monoclonal or Polyclonal
产品应用 WB、ELISA、IHC-P、IHC-F、Flow-Cyt、IF、IP、ICC 此产品应用不做依据，具体产品应用与实验稀释比请！021-6034 0810

not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

性    状 Lyophilized or Liquid
浓    度 1mg/1ml
亚    型 IgG
纯化方法 affinity purified by Protein G
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.


     Anti-pro-caspase-3抗体,半胱天冬酶3酶原抗体产品介绍： Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a prodomain, and large and small catalytic subunits. The active forms of caspases are generated by several stimuli including ligand-receptor interactions, growth factor deprivation and inhibitors of cellular functions. All known caspases require cleavage adjacent to aspartates to liberate one large and one small subunit, which associate into a2b2 tetramer to form the active enzyme. Gene for Caspase 3 also known as Yama, CPP32, and apopain codes for a 32-kDa protein. Caspase 3 cleaves the death substrate poly(ADP-ribose) polymerase (PARP) to a specific 85 kDa form observed during apoptosis and is inhibitable by the CrmA protein. Other Caspase 3 substrates include DNA-PK, actin, GAS2, and procaspase-6, etc. Caspase 3 is activated by cleavage events at Asp-28/Ser-29 (between N-terminal pro-domain) and Asp-175/Ser-176 (between large and small subunits) to generate a large subunit of 17-kDa and a small subunit of 12-kDa.

 此相关标记有：Alexa Fluor 350 标记、Alexa Fluor 488 标记、Alexa Fluor 555 标记、Alexa Fluor 647 标记、AP标记、APC标记、Biotin标记、Cy3标记、Cy5标记、Cy5.5标记、Cy7标记、FITC标记、Gold标记、HRP标记、PE标记、PE-Cy3标记、PE-CY5标记、PE-CY5.5标记、PE-CY7标记、RBITC标记 

    相关产品：

RABL2A RABL2A蛋白抗体
RAD26L/C9orf102 9号染色体开放阅读框102抗体
RAD51AP1 RAD51相互作用蛋白1抗体
RAD51D RAD51D蛋白抗体
Rad51L1 Rad51样蛋白1抗体
RAI14 维甲酸诱导蛋白14抗体
RAG1AP1 RAG1激活蛋白1抗体
RANBP6 RAN结合蛋白6抗体
RASGRP4 Ras蛋白特异*核苷酸释放因子4抗体
RASA4 GTP酶激活蛋白样RASA4抗体
RASEF ras基因相关蛋白Rab45抗体
RASGEF1C RASGEF1C蛋白抗体
RASGRP2 Ras蛋白特异*核苷酸释放因子2抗体
RASGRP3 Ras蛋白特异*核苷酸释放因子3抗体
phospho-RASGRP3 (Thr133) 磷酸化Ras蛋白特异*核苷酸释放因子3抗体
RASL12 RAS样蛋白12抗体
RAVER2 PTB结合核蛋白2抗体
RBBP7/RbAp46 组蛋白结合蛋白RBBP7抗体
SGSM2 小G蛋白信号调节蛋白2抗体
SH2D1B EAT2蛋白抗体
SH2D4A 含SH2结构域蛋白D4A抗体