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【中文名称】：BRCA1 Polyclonal Antibody
【英语名称】：BRCA1 Polyclonal Antibody
【产品类型】：一抗
【中文名称】：BRCA1 Polyclonal Antibody?
【英语名称】：BRCA1 Polyclonal Antibody
【产品类型】：一抗
【供应商】：Abbkine
【产品货号】：ABP50789
【产品规格】：30ul/100ul/200ul
【背景资料】：BRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein(BRCA1, DNA repair associated)combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximay 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified
蛋白别名为：BRCA1; RNF53; Breast cancer type 1 susceptibility protein; RING finger protein 53;基因ID为：672；蛋白质ID:P38398
【应用类型】：WB，IHC-p，IF，ELISA
补充：*的抗体稀释比例需要基于客户实验进行优化.建议的起始稀释比例如下: WB: 1:500-1:2000, IHC-p: 1:100-1:300, IF: 1:200-1:1000, ELISA: 1:5000. Not yet tested in other applications.
【免疫原】：合成多肽：human BRCA1 around the non-phosphorylation site of S1423.
【来源宿主】：兔
【反应性】：人，大鼠
【保存建议】：厂家*蓝冰运输.在发货后能在-20℃保存1年.为zui大限度的避免损失，请在打开管盖之前融化抗体并离心.我们建议使用前分装以避免反复冻融.
本产品为液体形式,溶解于PBS缓冲液中，含50%甘油，0.5%BSA和0.02%*.
【产品说明】：点击：BRCA1 Polyclonal Antibody??查看更详细产品说明，更多应用、储存、价格、货期等信息请Abbkine中国区域*总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看每日生物评论。
Abbkine致力于为生命科学研究和医疗发展提供的产品和技术。Abbkine设计、开发、生产并销售了一系列*的产品，包括生命科学领域研究相关的抗体、研究试剂以及细胞功能分析产品。Abbkine的产品为科学研究中的挑战提供卓有成效的解决方案，从而为的科学家节省时间并提高研究效率。作为Abbkine的中国区域总代理，艾美捷科技有限公司凭借丰富的专业经验，将一如既往的为中国区域客户提供Abbkine优质的产品和技术服务。
艾美捷科技有限公司品线覆盖生物研究各个领域，主要包括：分子生物学（核酸蛋白研究工具、cDNA/RNA、转染试剂、植物组培/细胞培养、生化试剂及试剂盒），试剂药品（蛋白酶抑制剂、化合物、荧光染料/探针、动物血清）、抗体（一抗、二抗、封闭血清）， 蛋白及试剂盒（细胞因子/重组蛋白、细胞凋亡/代谢/损伤、表观遗传、天然免疫）等。艾美捷为您寻找并提供*的产品解决方案、zui完备的物流服务、zui及时的售后服务。如果您对上述产品线感兴趣，请致电免费到艾美捷垂询相关产品信息及完整实验解决方案。
产品标签:BRCA1 (phospho Ser1423) Polyclonal Antibody，BRCA1 Polyclonal Antibody
