俾氏麦棕Y号：10114-58-6

俾氏麦棕Y号：10114-58-6   
英文名称：Bismarck brown Y；Vesuvine；Phenylene brown；Bismark brown G；C.I. 21000    
其他名称：俾士麦棕Y；俾斯麦棕TDR；俾斯麦棕GG；俾斯麦棕Y；毕士麦棕Y；碱性棕1；4,4'-[1,3-苯基双(偶氮)]双[1,3-苯二胺]盐酸盐；俾麦棕；碱性棕G；盐基棕；碱性棕Ⅰ   
号：10114-58-6    
C18H18N8?2HCl=419.31   
级别：BS   
熔点：≥300℃   
λmax ：457 nm   
性状(以下信息仅供参考)：棕色至黑棕色粉末。易溶于水呈黄光棕色，微溶于乙醇和溶纤素，不溶于丙同、苯、四录化碳；遇浓硫酸呈棕色，稀释后为红光棕色。遇硝酸呈橙色转为黄色，其水溶液加盐酸不变色，加10%氢氧化钠液呈橙色沉淀   
用途：本品仅供科研，不得用于其它用途。   
保存：RT 俾氏麦棕Y号：10114-58-6储存条件：
避光、干燥阴凉处封闭贮存,严禁与有毒、有害物品混放、混运。本品为非危险 产品可按一般化学品运输,轻搬动轻放,防止日晒、雨淋！受热、受潮、受光后易丧失活力,保存期短,因此贮存和运输条件比较苛刻。
运输：汽车运输、EMS邮政快递，申通快递等， 款到上海3天内发货； 
售后：如您对我们的产品服务及技术指标有特殊要求，请及时通知我方。 
存储：应贮存在干燥清洁避光的环境中，严禁与有毒物质混放，以免污染（保质期为两年）。 
俾氏麦棕Y号：10114-58-6主要优级纯、分级纯和化学纯3种：
（1）优级纯（GR：Guaranteed reagent），又称一级品或保证试剂，99.8%，这种试剂纯度Z高，杂质含量Z低，适合于重要精密的分析工作和科学研究工作，使用绿色瓶签。
（2）分析纯（AR），又称二级试剂，纯度很高，99.7%，略次于优级纯，适合于重要分析及一般研究工作，使用红色瓶签。
（3）化学纯（CP），又称三级试剂，≥ 99.5%，纯度与分析纯相差较大，适用于工矿、学校一般分析工作。使用蓝色（深蓝色）标签。
（4）实验试剂（LR：Laboratory reagent），又称四级试剂。
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Gaucher disease, schizophrenia and Usher syndrome, map to chromosome 1.
Function : Displays neurotrophic activity and activates phosphorylation of MAPK1/ERK2, MAPK3/ERK1 and AKT1/AKT in primary cultured neurons. Does not have mitogenic activity in primary cultured astrocytes. May play a role on neuronal differentiation and may have a transient effect on neural cell proliferation in neural precursor cells. Neurotrophic activity is enhanced by binding to heme.
Subcellular Location : Secreted > extracellular space.
Similarity : Belongs to the cytochrome b5 family. MAPR subfamily.
Contains 1 cytochrome b5 heme-binding domain.
Database links : UniProtKB/Swiss-Prot: Q9UMX5.1
英文名称  Anti-Neuronatin
中文名称  胚胎神经细胞NNAT抗体
别    名  Neuronatin; Nnat; NNAT_HUMAN; Peg 5; Peg5.
浓    度  1mg/1ml
规 格  0.2ml/200μg
抗体来源  Rabbit 
克隆类型  polyclonal
交叉反应  Human, Mouse, Rat, Pig, Cow, Rabbit
产品类型  一抗   
研究领域  肿瘤 细胞生物 发育生物学 神经生物学 细胞分化 
蛋白分子量  predicted molecular weight: 9kDa
性    状  Lyophilized or Liquid
免 疫 原  KLH conjugated synthetic peptide derived from human Neuronatin
亚    型  IgG
纯化方法  affinity purified by Protein A
储 存 液  Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用   WB=1:100-500  ELISA=1:500-1000  IHC-P=1:100-500  IHC-F=1:100-500  ICC=1:100-500  IF=1:100-500
（石蜡切片需做抗原修复）
 not yet tested in other applications.
 optimal dilutions/concentrations should be determined by the end user. 
保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 The paternally imprinted Neuronatin gene (NNAT) is initially expressed in rhombomeres and the pituitary gland and is later expressed more widely, but much less abundantly, in the central and peripheral nervous systems. The human NNAT gene maps to chromosome 20q11.23 and contains an imprinting region associated with morphological abnormalities and early neonatal lethality. Specifically, hypermethylation of the NNAT gene occurs in both myeloid and lymphoid acute pediatric leukemias and may inhibit NNAT expression. The Neuronatin protein consists of two isoforms, alpha and beta, which are the products of alternative splicing. The alpha form of the Neuronatin gene is encoded by three exons, whereas the beta form is missing the second exon. Neuronatin mRNA expression is abundant in undifferentiated PC-12 cells. Treatment of these cells with nerve growth factor (NGF), which contributes to neuronal differentiation, downregulates Neuronatin mRNA expression. NNAT (-) 1.9 PC-12 cells exhibit an increase in nigericin, rotenone and valinomcin sensitivity; NNAT transfection restores wild-type PC-12 resistance. These results suggests a potential protective role for Neuronatin against toxic insult during development.
Function : May participate in the maintenance of segment identity in the hindbrain and pituitary development, and maturation or maintenance of the overall structure of the nervous system. May function as a regulatory subunit of ion channels.
Similarity : Belongs to the neuronatin family.
英文名称  Anti-NPY5R
中文名称  神经肽Y受体5抗体
别    名  Neuropeptide Y receptor type 5; Neuropeptide Y receptor Y5; NPY 5R; NPY R5; NPY Y5; NPY Y5 receptor; NPY-Y5 receptor; NPY5 R; NPY5-R; NPY5R; NPY5R_HUMAN; NPYR 5; NPYR5; NPYY 5; NPYY5; NPYY5-R; Y5 receptor.
浓    度  1mg/1ml
规 格  0.2ml/200μg