瘦素受体重叠转录基因1抗体,Anti-LEPROTL1抗体简单介绍:
产品编号:BYK-18234R
英文名称:Anti-LEPROTL1
中文名称:瘦素受体重叠转录基因1抗体
别名:HSPC112; Leprotl1; Leptin receptor overlapping transcript-like 1; LERL1_HUMAN; my047; Vps55
背景介绍:Mutation of Ob (Obesity factor), also known as leptin precursor, results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. The Ob gene product may function as a component of a signaling pathway in adipose tissue that functions to regulate body fat depot size. The leptin receptor, designated Ob-R, has been shown to be a single membrane-spanning receptor that most resembles the gp130 signal transducing component of the IL-6, G-CSF and LIF receptor. LEPROTL1 (Leptin receptor overlapping transcript-like 1) is a 131 amino acid multi-pass membrane protein that is highly homologous to the leptin receptor gene-related protein, Ob-R. LEPROTL1 is widely expressed and contains a JAK binding site. The LEPROTL1 gene is located on chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes.
产品规格:50ul;100ul;200ul;1ml,*
抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请或添加客服直接索取)
性 状 Lyophilized or Liquid
浓 度 1mg/ml
瘦素受体重叠转录基因1抗体,Anti-LEPROTL1抗体产品信息:
冰冻切片的免疫组化染色步骤
- 速冻组织
- 冰冻切片4~8μm,冰冻切片后如不染色,必须吹干,储存低温冰箱内,或进行短暂预固定后储存于-20℃冰箱
- 室温放置30分钟后,入4℃丙酮固定10分钟,也可根据需要选择其他的固定方式
- PBS冲洗,5分钟×3次
- 用3%过氧化氢孵育5~10分钟,消除内源性过氧化物酶的活性
- PBS冲洗,5分钟×3次
- 下接石蜡切片免疫组化染色操作步骤(滴加一抗开始)
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