背景介绍:This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4
别名:CCL2_HUMAN; C-C motif chemokine 2; HC11; Monocyte chemoattractant protein 1; Monocyte chemotactic and activating factor; MCAF; Monocyte chemotactic protein 1; MCP-1; Monocyte secretory protein JE; Small-inducible cytokine A2.
淋巴细胞趋化因子CCL2抗体,Anti-CCL2抗体简单介绍:
产品编号:BYK-20201R
英文名称:Anti-CCL2
中文名称:淋巴细胞趋化因子CCL2抗体
产品规格:50ul;100ul;200ul;1ml,*
抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请或添加客服直接索取)
性 状 Lyophilized or Liquid
浓 度 1mg/ml
淋巴细胞趋化因子CCL2抗体,Anti-CCL2抗体产品信息:
博研生物小课堂:
常用激光器对应荧光素的选择:
蓝色激光器荧光素(488nm):Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7
红色激光器荧光素(633nm):APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647
黄色激光器荧光素(561nm):PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594
1.阳性细胞染色分布有三种类型:细胞浆、细胞核、细胞膜表面。大部分抗原见于细胞浆,可见于整个胞浆或部分胞浆
2.阳性细胞分布可分为灶型和弥漫性
3.由于细胞内含抗原量不同,所以染色强度不一。如果细胞之间染色强度相同,常提示其反应为非特异性
4.阳性细胞染色定位于单个细胞,且与阴性细胞相互交杂分布;而非特异性染色常不限于单个细胞,而是累及一片细胞。
5.切片边缘、刀痕或褶皱区域,坏死或挤压的细胞区,胶原结缔组织等,常表现为相同的阳性染色强度,不能用于判断阳性。
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