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目录:珀金埃尔默企业管理(上海)有限公司>> Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 10µCi

Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 10µCi
  • Vasoactive Intestinal Polypeptide (human, porcine, rat), [125I], 10µCi
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更新时间:2023-10-20 07:26:11浏览次数:312评价

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Vasoactive intestinal polypeptide (VIP), labeled with 125I. VIP binds vasoactive intestinal peptide receptors VPAC1 and VPAC2, a group of GPCRs that are potential drug targets for nervous and endocrin......

We offer radioligands and radiolabeled biomolecules to use as tracers, for radioimmunoassays (RIAs), for autoradiographic visualization, or for performing saturation and competition radioligand binding assays to determine receptor expression levels (Bmax), dissociation constants (Kd), association and dissociation rates (kon and koff), and inhibitor constants (Ki) for a variety of receptors. We develop our radioligands to the highest specific activity possible and provide high purity resulting in low non-specific binding products. Each of our ultra-pure radiolabeled compounds is fully characterized for pharmacological action and validated in binding assays.

Radiochemicals remain the most sensitive method for probing binding biology; yielding unprecedented sensitivity gives results that technicians and scientists can trust. For over 50 years, PerkinElmer has been a leading supplier of New England Nuclear (NEN) radiochemicals, liquid scintillation cocktails, vials and nuclear counting detection instruments.

References for NEX192:

  1. Broner, C.W., O'Dorisio, M.S., Rosenberg, R.B., O'Dorisio, T.M. (1995), Cyclic nucleotides and vasoactive intestinal peptide production in a rabbit model of Escherichia coli septicemia. Am J Med Sci, 309 (5): 267-277.
  2. Lilling, G., Wollman, Y., Goldstein, M.N. et al. (1994), Inhibition of human neuroblastoma growth by a specific VIP antagonist, J Mol Neurosci 5: 231-239.

规格

浓度<1.0>
检测方法Radiometric
新鲜的很多天Fourth Monday of each month
标签位置Nominally Labeled
产品品牌名称NEN Radiolabeled Ligands
放射性同位素I-125
放射性核素125I
受体类型Vasoactive Intestinal Peptide
运输条件环境
特殊订购信息This is a radioactive product - shipping address must have a license to receive radioactive materials.
治疗领域CNS & Neurologic, Cardiovascular, Inflammation
产品尺寸10 µCi

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