活化B淋巴细胞因子1抗体；Anti-MSC/Musculin抗体 返回列表页

活化B淋巴细胞因子1抗体；Anti-MSC/Musculin抗体产品信息：

背景介绍：Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins, known to play an important role in the regulation of muscle cell development, includes Myo D, myogenin and musculin (also designated MyoR). Members of this group of transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E or musculin-E heterodimers bind avidly to consensus E box motifs, which are functionally important elements in the promoter regions of many muscle-specific terminal differentiation genes. Myo D complexes potently induce transcriptional activation, while musculin complexes bind adjacent to Myo D DNA-binding regions to represses Myo D activity, which then results in the delayed expression of muscle-specific genes. Musculin is highly expressed in undifferentiated and proliferating myoblasts in culture, and its expression is down regulated during myogenesis and at the onset of terminal differentiation.

英文名称：Anti-MSC/Musculin
中文名称：活化B淋巴细胞因子1抗体

活化B淋巴细胞因子1抗体；Anti-MSC/Musculin抗体简单介绍：

产品编号：BYK-17847R

别名：ABF-1; ABF1; Activated B cell factor 1; Activated B-cell factor 1; bHLHa22; Class A basic helix-loop-helix protein 22; Msc; MUSC_HUMAN; Musculin; MYOR.  

抗体来源 Rabbit or Mouse

克隆类型 Polyclonal or Monoclonal

交叉反应、产品应用 （具体交叉反应与产品应用请或添加客服直接索取）

分 子 量 21kDa
细胞定位 细胞核

性    状 Lyophilized or Liquid
浓    度 1mg/ml

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