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线粒体LETM2抗体,Anti-LETM2抗体简单介绍:
产品编号:BYK-18225R
英文名称:Anti-LETM2
中文名称:线粒体LETM2抗体
别名:LETM1 and EF hand domain containing protein 2; LETM1 and EF-hand domain-containing protein 2; LETM1 domain containing protein LETM2 mitochondrial; LETM1 domain-containing protein LETM2; Letm2; LETM2_HUMAN; Leucine zipper EF hand containing transmembrane protein 1 like; Leucine zipper EF hand containing transmembrane protein 2; Leucine zipper-EF-hand-containing transmembrane protein 1-like; mitochondrial.
背景介绍:LETM2 is a 491 amino acid protein that is localized to the mitochondrial membrane and contains one LETM1 domain. Despite its name, LETM2, which is preferentially expressed in sperm and testis, does not contain any EF-hand domains. There are four isoforms of LETM2 that are produced as a result of alternative splicing events. A homolog of LETM2, LETM1 is thought to be involved in maintaining normal mitochondrial function and overall cell viability. Deletions in the gene encoding LETM1 are associated with Wolf-Hirschhorn syndrome (WHS), a congenital syndrome characterized by a number of abnormalities, including mental retardation, seizures, heart defects, fused teeth, hearing loss, a webbed neck and renal abnormalities. The LETM2 gene is located on chromosome 8, which is made up of nearly 146 million bases and encodes about 800 genes.
产品规格:50ul;100ul;200ul;1ml,*
抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请或添加客服直接索取)
性 状 Lyophilized or Liquid
浓 度 1mg/ml
线粒体LETM2抗体,Anti-LETM2抗体产品信息:
冰冻切片的免疫组化染色步骤
- 速冻组织
- 冰冻切片4~8μm,冰冻切片后如不染色,必须吹干,储存低温冰箱内,或进行短暂预固定后储存于-20℃冰箱
- 室温放置30分钟后,入4℃丙酮固定10分钟,也可根据需要选择其他的固定方式
- PBS冲洗,5分钟×3次
- 用3%过氧化氢孵育5~10分钟,消除内源性过氧化物酶的活性
- PBS冲洗,5分钟×3次
- 下接石蜡切片免疫组化染色操作步骤(滴加一抗开始)
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