MARCKS样蛋白1抗体,Anti-MARCKSL1抗体 返回列表页

背景介绍：This gene encodes a member of the myristoylated alanine-rich C-kinase substrate (MARCKS) family. Members of this family play a role in cytoskeletal regulation, protein kinase C signaling and calmodulin signaling. The encoded protein affects the formation of adherens junction. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are located on the long arm of chromosomes 6 and 10.

Function:
Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May also affect cancer cell migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems.

别名：F52; Mac MARCKS; Mac-MARCKS; MacMARCKS; Macrophage enriched Myristoylated Alanine Rich C Kinase Substrate Like Protein; Macrophage myristoylated alanine-rich C kinase substrate; MARCKS like 1; MARCKS like protein 1; MARCKS related protein; MARCKS-like protein 1; MARCKS-related protein; MARCKSL1; MLP; MLP1; MRP; MRP_HUMAN.  

MARCKS样蛋白1抗体,Anti-MARCKSL1抗体简单介绍：

产品编号：BYK-18678R

英文名称：Anti-MARCKSL1
中文名称：MARCKS样蛋白1抗体

产品规格：50ul；100ul；200ul；1ml，*

抗体来源 Rabbit or Mouse

克隆类型 Polyclonal or Monoclonal

交叉反应、产品应用 （具体交叉反应与产品应用请或添加客服直接索取）

性    状 Lyophilized or Liquid
浓    度 1mg/ml

MARCKS样蛋白1抗体,Anti-MARCKSL1抗体产品信息：

各种HRP酶标记成抗体的效价测定程序如下（如：羊抗鼠IgG-HRP的效价测定）：

1、抗原包板：15ug/ml 小鼠IgG-pH9.6·CB液 0.1ml/孔；

2、37°C包被60min或4°C过夜；

3、PBST洗板3次，5min/次；

4、加入倍比稀释的HRP标记抗体 0.1ml/孔；

5、37°C 30min；

6、PBST洗板5min/次×3；

7、底物液0.1ml/孔 37°C 5-10min；

8、终止液：2N H2SO4 0.05ml/孔；

9、450nm 测定OD值；

阳性OD值比对照值大3倍，为判断效价稀释度。

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