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背景介绍:This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
别名:DNC; MCPHA; Mitochondrial thiamine pyrophosphate carrier; Mitochondrial uncoupling protein 1; MUP1; Solute carrier family 25 (mitochondrial deoxynucleotide carrier) member 19; Solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier) member 19; Solute carrier family 25 member 19; TPC.
线粒体解偶联蛋白1抗体,Anti-MUP1抗体简单介绍:
产品编号:BYK-19106R
英文名称:Anti-MUP1
中文名称:线粒体解偶联蛋白1抗体
产品规格:50ul;100ul;200ul;1ml,*
抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请或添加客服直接索取)
性 状 Lyophilized or Liquid
浓 度 1mg/ml
线粒体解偶联蛋白1抗体,Anti-MUP1抗体产品信息:
博研生物小课堂:
常用激光器对应荧光素的选择:
蓝色激光器荧光素(488nm):Alexa Fluor 488、FITC、PerCP、PerCP-Cy5.5、PE、PE-Cy5.5、PE-Cy5、PE-Cy7
红色激光器荧光素(633nm):APC、Cy5、APC-Cy5.5、APC-Cy7、Alexa Fluor 647
黄色激光器荧光素(561nm):PE、PE-Cy5.5、PE-Cy5、PE-Cy7、Cy3、Alexa Fluor 555、Alexa Fluor 594
显色观察
免疫酶染色应注意控制:
1. 呈色质浓度和反应时间。增加成色质的量和(或)增加底物反应时间,可增加反应产物强度;着色太深可减少反应时间。
2. 过氧化物酶显色时,H2O2浓度较大将使显色反应过快而至背景加深;过量H2O2可能抑制酶的活性。
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Anti-Notch1/MOTC 跨膜受体蛋白Notch-1抗体
Anti-BEGAIN/SAPAP 大脑富含鸟苷酸激酶相关蛋白抗体
Anti-NOS-3/eNOS 一氧化氮合成酶-3(内皮型)抗体
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Anti-P2Y12 G蛋白偶联嘌呤受体p2y12抗体
Anti-NOS-2/iNOS 一氧化氮合成酶-2抗体(诱导型)
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