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Anti-SIAH3抗体,SIAH3蛋白抗体说明资料

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更新时间:2016-01-22 09:42:08浏览次数:107次

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     Anti-SIAH3抗体,SIAH3蛋白抗体说明资料产品介绍:Members of the SINA (seven in absentia) protein family are components of ubiquitin ligase complexes, which target proteins for proteasomal degradation. SIAH3 (seven in absentia homolog 3) is a 269 amino acid protein that belongs to the SINA family, contains one SIAH-type zinc finger and is encoded by a gene located on human chromosome 13. Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. 

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保存条件:Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
连续使用时4°C存储,保质期六个月,*存储时建议分装为10ul以上小包装-20°C存储,并避免反复冻融,保质期一年。

 

产品名称 Anti-SIAH3抗体,SIAH3蛋白抗体说明资料

产品编号 BYK-17481R

英文名称 SIAH3
中文名称 SIAH3蛋白抗体
别    名 FLJ39203; Gm912; RP11-480G1.1; Seven in absentia homolog 3; Siah-3; SIAH3; SIAH3_HUMAN.
研究领域 肿瘤  细胞生物  免疫学  神经生物学               

抗体来源 Rabbit or Mouse
克隆类型 Polyclonal or Monoclonal
交叉反应、产品应用 (具体交叉反应与产品应用请)

 

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