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491次Anti-IL-1抗体供应商
From:Abcam
Catalog Number : BYK-51035R
Quantity size : 0.1ml (1mg/ml,Lyophilized or Liquid.Buffer=0.01M PBS,ph 7.4 with 10 mg/ml BSA and 0.1% Sodium azide.Reconstitute with 0.1ml sterile distilled water.)
background: IL-1(Interleukin-1) is a cytokine responsible for initiating a variety of activities through the activation of transcription factors,NFκB and AP-1,thereby promoting host response to injury or infection.The IL-1superfamily is comprised of several ligands and receptors. IL-1F5,also know as IL-1δ,IL-1 like protein 1(IL-1L1),IL-1HY1,IL-1ra(receptor antagonist) homolog 1 or IL-1 ralated protein 3(IL-1rp3), is a secreted ligand belong to this superfamily.IL-1F5 is expressed in monocytes and macrophages and is activated by endotoxins. It shares 47% sequence identity with IL-1ra and similary lacks the loop between the fourth and fifth β-strands. IL-1Fcts as an antagonist, inhibiting the IL-1F9 activation of NFκB. Similar to other family members, IL-1F5 can be regulated by bacterial lipopolysaccharide(LPS).
Specificity :
Application :
Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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