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甜蜜素号:139-05-9
英文名称:Sodium Cyclamate;Sodium N-cyclohexylsulfamate
其他名称:环己基氨基磺酸钠;环氨酸钠;环拉酸钠;甜密素;环己胺磺钠;环己烷氨基磺酸钠
号:139-05-9
C6H12NNaO3S=201.22
级别:BR
含量:≥98.0%
PH:5.5~7.5
干燥失重:≤1.0%
重金属:≤10ppm
性状(以下信息仅供参考):白色结晶或结晶性粉末。分解温度约280℃,不发生焦糖化反应,溶于水(1g/5ml)丙二醇(1g/25ml),几乎不溶于乙醇,乙迷,苯和方。10%水溶液PH为5.5-7.5。对热,光,空气稳定,碱性下稳定,酸性时略有分解。味甜,加热有略有苦味
用途:本品仅供科研,不得用于其它用途。
保存:RT,避光甜蜜素号:139-05-9储存条件:
避光、干燥阴凉处封闭贮存,严禁与有毒、有害物品混放、混运。本品为非危险 产品可按一般化学品运输,轻搬动轻放,防止日晒、雨淋!受热、受潮、受光后易丧失活力,保存期短,因此贮存和运输条件比较苛刻。
运输:汽车运输、EMS邮政快递,申通快递等, 款到上海3天内发货;
售后:如您对我们的产品服务及技术指标有特殊要求,请及时通知我方。
存储:应贮存在干燥清洁避光的环境中,严禁与有毒物质混放,以免污染(保质期为两年)。
甜蜜素号:139-05-9主要优级纯、分级纯和化学纯3种:
(1)优级纯(GR:Guaranteed reagent),又称一级品或保证试剂,99.8%,这种试剂纯度Z高,杂质含量Z低,适合于重要精密的分析工作和科学研究工作,使用绿色瓶签。
(2)分析纯(AR),又称二级试剂,纯度很高,99.7%,略次于优级纯,适合于重要分析及一般研究工作,使用红色瓶签。
(3)化学纯(CP),又称三级试剂,≥ 99.5%,纯度与分析纯相差较大,适用于工矿、学校一般分析工作。使用蓝色(深蓝色)标签。
(4)实验试剂(LR:Laboratory reagent),又称四级试剂。
产品类型 一抗
研究领域 细胞生物 信号转导 生长因子和激素 转录调节因子 激酶和磷酸酶
蛋白分子量 predicted molecular weight: 47kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Human SNX5 (2-75aa)
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that interact with a variety of receptor types and are involved in intracellular trafficking (1). SNX1 and the related splice variant, SNX1A, bind the epidermal growth factor (EGF) receptor, facilitate its transport to lysosome, and thereby contribute to the degradation of the receptor (2,3). SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).
Function : May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation.
甜蜜素号:139-05-9Subunit : Interacts with SNX1; this promotes location at the endosome membrane.
Subcellular Location : Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle. Note=Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2). Detected on macropinosomes. Targeted to membrane ruffles in response to EGFR stimulation.
Similarity : Belongs to the sorting nexin family.
Contains 1 BAR domain.
Contains 1 PX (phox homology) domain.
Database links : UniProtKB/Swiss-Prot: Q9Y5X3.1
英文名称 Anti-SNX2
中文名称 分选连接蛋白2抗体
别 名 MGC5204; SNX 2; SNX2; SNX2_HUMAN; Sorting nexin 2; Sorting nexin-2; Transformation related gene 9 protein; Transformation-related gene 9 protein; TRG 9; TRG-9; TRG9.
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
产品类型 一抗
研究领域 细胞生物 信号转导 生长因子和激素 转录调节因子 细胞膜受体
蛋白分子量 predicted molecular weight: 58kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from Human SNX2
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Sorting nexin 1 (SNX1) is a member of a large family of hydrophilic proteins that inte