NUCLEODUR 高纯硅胶键合相液相色谱柱

NUCLEODUR--新一代对称的硅球
NUCLEODUR 是采用合成，并在严格工艺控制下生产的硅球。使它具有近乎的球型表面。从下图中可以看到NUCLEODUR 的硅球表面十分光滑对称和均匀的粒度大小分布。

研究表明液相色谱硅球中除了硅醇基活性基团外，金属杂质，如铁，钠等的存在，同样会与被测样品中的胺和酚类化合物产生吸附，影响分析结果。

NUCLEODUR 不但严格控制硅球表面的硅醇基团，还特别成功地消除了硅球内的金属杂质。

右表是使用AAS（原子吸收）方法检测NUCLEODUR 100A-5um 规格的硅球，显示其金属杂质含量极低。

Summary of available NUCLEODUR® phases

Phase

Modification

% C

pH range

Particle sizes [μm]

USP

Structure

C18 Gravity

octadecyl, high density coating, multi-endcapping

18

1–11

1.8 · 3 · 5

L1

C8 Gravity

octyl, high density coating, multi-endcapping

11

1–11

1.8 · 5

L7

C18 Isis

octadecyl, specially cross-linked modification, endcapped

20

1–10

1.8 · 3 · 5

L1

C18 Pyramid

octadecyl with polar endcapping

14

1–9

1.8 · 3 · 5

L1

PolarTec

octadecyl with embedded polar group

17

1–9

1.8 · 3 · 5

L1 L60

Phenyl-Hexyl

special phenylhexyl phase

10

1–10

1.8 · 3 · 5

L11

PFP

pentafluorophenyl-propyl with multi-endcapping

8

1–9

1.8 · 3 · 5

L43

Sphinx RP

bifunctional, balanced ratio of propylphenyl and octadecyl, endcapping

15

1–10

1.8 · 3 · 5

L1 L11

C18 HTec

octadecyl, high density coating, high capacity, multi-endcapping

18

1–11

1.8 · 3 · 5
7 · 10

L1

C18 ec

octadecyl, medium density, endcapping

17.5

1–9

3 · 5
ａnd larger

L1

C8 ec

octyl, medium density, endcapping

10.5

1–9

3 · 5

L7

HILIC

ammonium – sulfonic acid

7

2–8.5

1.8 · 3 · 5

CN/CN-RP

cyano (nitrile) for NP and RP separations

7

1–8

3 · 5

L10

NH2/NH2-RP

aminopropyl for NP and RP separations

2.5

2–8

3 · 5

L8

SiOH

unmodified NUCLEODUR®

–

2–8

3 · 5
ａnd larger

L3