“乳癌相关抗原抗体,Anti-CA153/Mucin 1抗体”应用于IHC、WB、 IF、IP、ELISA,质量保证,无效免费退换,另外本公司生产经营各种标记二抗、免疫印迹常用试剂、免疫组化常用试剂,咨询!
产品介绍:
【产品名称】:乳癌相关抗原抗体,Anti-CA153/Mucin 1抗体
【产品类型】:一抗
【产品编号】:BYk-1239R
【相关标记】: HRP Biotin Gold RBITC AP FITC Cy3 Cy5 Cy5.5 Cy7 PE PE-Cy3 PE-CY5 PE-CY5.5 PE-CY7 APC Alexa Fluor 350 Alexa Fluor 488 Alexa Fluor 555 Alexa Fluor 647
【性 状】: Lyophilized or Liquid
【浓 度】: 1mg/1ml
【亚 型】: IgG
【规 格】:0.1ml/100ug,0.2ml/200ug
【抗体来源】: Rabbit OR MOUSE
【克隆类型】: polyclonal or monoclonal
【产品用途】:科研实验,用于免疫组化实验,WB实验、IF、IP、ELISA实验,相应的标记抗体有HRP标记抗体,FITC标记,BIO等。
【贮 存】: Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
【详细介绍】:MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90% breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
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